From the Journals: ADHD Recovery May Depend On How the Brain Develops The way the cerebral cortex develops may determine who recovers from childhood attention-deficit/hyperactivity disorder and whose disorder continues into adulthood, according to a study published in the Oct. 2013 issue of Biological Psychiatry (bit.ly/adhd-recovery). These results may be the first step in developing tools to predict reliably the outcomes ... From the Journals
Free
From the Journals  |   January 01, 2014
From the Journals: ADHD Recovery May Depend On How the Brain Develops
Author Notes
Article Information
Attention, Memory & Executive Functions / From the Journals
From the Journals   |   January 01, 2014
From the Journals: ADHD Recovery May Depend On How the Brain Develops
The ASHA Leader, January 2014, Vol. 19, online only. doi:10.1044/leader.FTJ5.19012014.np
The ASHA Leader, January 2014, Vol. 19, online only. doi:10.1044/leader.FTJ5.19012014.np
ADHD Recovery May Depend On How the Brain Develops
The way the cerebral cortex develops may determine who recovers from childhood attention-deficit/hyperactivity disorder and whose disorder continues into adulthood, according to a study published in the Oct. 2013 issue of Biological Psychiatry (bit.ly/adhd-recovery). These results may be the first step in developing tools to predict reliably the outcomes of childhood ADHD.
Researchers knew from prior work that cortical structure is thinner in adults with ADHD, particularly in regions of the brain that play important roles in cognitive functioning and attention. However, that work was cross-sectional—that is, conducted at a single point in time—so changes over time weren’t captured. The authors focused on those same regions in this study, but conducted a longitudinal study so they could link symptoms’ trajectories with brain development trajectories— particularly the structure of cortical regions that control attention.
A team led by Philip Shaw at the National Human Genome Research Institute recruited 92 children with ADHD (mean age 11), who underwent repeated structural imaging scans and clinical assessments for more than a decade, including as adults (mean age 24). For comparison, they also scanned 184 volunteers without ADHD.
The team found that ADHD continued into adulthood in 37 (40 percent) of the participants diagnosed with childhood ADHD, and these individuals showed increased rates of cortical thinning. In contrast, the cortical thickness of individuals who achieved remission of their ADHD developed toward the normal range.
“We find that differences in patterns of brain growth are linked with differences in the adult outcome of childhood ADHD. Differences in these regions—specifically a thinner cortex—are found in childhood ADHD,” Shaw said. “However, for the group whose ADHD improved with age, these differences tend to resolve and by adulthood, these regions did not differ significantly from individuals who never had ADHD. By contrast, for the group with persistent ADHD, childhood differences persisted in the ‘attention’ regions of the brain.”
0 Comments
Submit a Comment
Submit A Comment
Name
Comment Title
Comment


This feature is available to Subscribers Only
Sign In or Create an Account ×
FROM THIS ISSUE
January 2014
Volume 19, Issue 1